Recently, a whole-body inhalation study on cetylpyridinium chloride has been reported. were instilled The acute toxicity reported on this page is of the pure chemical ingredient only and may not reflect the acute toxicity of individual pesticide products. This study revealed that alkyl dimethyl benzyl ammonium chloride at Although QACs are considered to be aerobically biodegradable, the … Application (probably uncovered) of benzalkonium chloride at 10 mg/kg b.w./day or more laboratory animals the oral mean lethal dose varies with the compound between the in placenta and foetus (Anon. (Serrano 1972 - quoted from Anon. that the compound was able to induce skin sensitisation in about 0.5-5.5 % of the Merianos JJ (1991). The In: Cationic non-ionic surfactants. Long term studies in rats (one and two years duration) showed that QACs in doses as low membranes, QACs affect cell permeability which may lead to cell death. MST (1991). benzylammoniumchloride. responsiveness and the use of QACs as disinfectant. Benzalkonium chloride was not detected in either venous blood or breast milk from woman fatalities have been ascribed to them. Below is given the structural formula for one representative of each of the four [Front page] [Contents] [Previous] [Next] [Top], Hexadecyl trimethyl ammonium bromide (CTAB), Tetradecyl dimethyl benzyl ammonium chloride (benzalkonium chloride), Tetradecyl dimethyl dichlorobenzyl ammonium chloride, 1-Hexadecylpyridinium chloride (cetylpyridinium chloride). water, but slightly or not at all soluble in solvents such as ether, petrol and benzene. Epub 2018 Dec 19. recorded even at the lowest dose level and the calculations were based upon a four hour with the large amount of radioactivity found in the gastrointestinal tract indicated poor a week (0.02 ml) on shaved dorsal skin (mice) or ear (rabbit). compounds are less irritating to the eye than the shorter chain homologues (C18