Federal government websites often end in .gov or .mil. 2022 Aug 12;13:970183. doi: 10.3389/fimmu.2022.970183. Leuk Res. [Aggressive natural killer cell leukemia/lymphoma--possible existence of a new clinical entity originating from the third lineage of lymphoid cells]. Would you like email updates of new search results? The most common patterns of post-relapse FISH dissimilarity were loss of previously detected hyperdiploidy, seen in three (33.3%) cases, and gain of 1q21 in three (33.3%) cases. . If you have a leukemia or lymphoma, routine tests such as a complete blood count (CBC) and a WBC differentialmay show an increased number of white blood cells with a predominance of one type.
Detection of Bcell populations with monotypic light chain expression Specimen must arrive within 96 hours of collection. A blood sample is obtained by inserting a needle into a vein.
Constrictive Pericarditis-A Cloak Camouflaging Lymphoma Diagnosis of malignant lymphoma - An overview. Acute Lymphoblastic Leukemia. Diagnosis of leukemia or lymphoma is based on the visual examination of a blood smear and/or bone marrow biopsy and aspiration for the presence of certain cell types. These antigens are protein structures found on or within WBCs. (2022, December 30). It is also suggested to have prognostic significance [ 2]. 1989 Dec;30(12):2134-40. NCI CPTC Antibody Characterization Program. Body fluid samples are obtained through collection of the fluid in a container or by inserting a needle into the body cavity and aspirating a portion of the fluid with a syringe. Accessed April 2011. Abstract. Morice WG, Kimlinger T, Katzmann JA, et al: Flow cytometric assessment of TCR-Vbeta expression in the evaluation of peripheral blood involvement by T-cell lymphoproliferative disorders: a comparison with conventional T-cell immunophenotyping and molecular genetic techniques. Available online at https://emedicine.medscape.com/article/990113-overview. Accessibility SI Abnormal Reports. Leuk Res. Immunophenotypic features of acute myeloid leukemia with inv(3)(q21q26.2)/t(3;3)(q21;q26.2). National Library of Medicine Flow cytometric analysis of the peripheral blood shows no immunophenotypic evidence for an abnormal B cell or T- cell population, and no circulating blasts. Leukemic myeloblasts expressed many leukocyte differentiation antigens, thus reflecting association with myeloid lineage and maturation level. government site. PMC 2016 Aug 2;11(8):e0158827. Submission of bilateral specimens is not required. with these terms and conditions. (2008 December 1). Williams and Wilkins Inc; 1994:939-969, 3. (2019 January, Updated).Acute Lymphoblastic Leukemia ALL. official website and that any information you provide is encrypted No immunophenotypic myeloid abnormalities were detected in the healthy donor bone marrow aspirates or in the 10 remission bone marrow aspirates from patients with a history of nonmyeloid neoplasia (Table 3). no immunophenotypic abnormalities detected FREE COVID TEST lansing school district spring break 2021 Book Appointment Now. Morphologic evaluation and flow cytometric immunophenotypic analysis revealed no evidence of plasma cell neoplasm involving the BM. Federal government websites often end in .gov or .mil. 2020 May-Aug;24(2):195-199. doi: 10.4103/0973-029X.294653. Accessed April 2011. (33%) and in 15 of 17 (v)SAA patients (88%). Pertinent clinical history including reason for testing or clinical indication. official website and that any information you provide is encrypted although diagnostic criteria are well established, a no immunophenotypic myeloid abnormalities were detected in the healthy donor bone marrow aspirates or in the 10 remission bone marrow aspirates from patients with a history of nonmyeloid neoplasia table 3, as mentioned, the immunophenotypic panels used evolved during the study, and not all The translocation t(9;22)(q34;q11.2) was detected by conventional chromosomal analysis in 59 patients (91%) the Ph-positive ALL cohort. Rereview of PB smears from these patients, who had typical cutaneous findings of MF, did not identify definitive Sezary cells. Flow cytometric immunophenotyping is a valuable addition to morphology in the diagnosis of MDS in adults.7 Abnormalities detected by flow cytometry in myelomonocytic, .
Available online at https://www.mayomedicallaboratories.com/test-catalog/Overview/3287. Would you like email updates of new search results? Immunophenotypically, both NHLs lacked surface Ig heavy chains. francis gray poet england services@everythingwellnessdpc.com (470)-604-9800 ; ashley peterson obituary Facebook. Jaffe, E. et. (2019 January 3, Updated). An ASCUS pap smear result is considered to be mildly abnormal. A total of 192 Chinese patients with acute myeloid leukemia (AML) were immunophenotyped by flow cytometry using a panel of monoclonal antibodies. Tests for Acute Lymphocytic Leukemia (ALL). Shi M, Ternus JA, Ketterling RP, et al: Immunophenotypic and laboratory features of t(11;14)(q13;q32)-positive plasma cell neoplasms. Mayo Clinic, Mayo Medical Laboratory [On-line information].
Myeloid Blast and Maturation Assessment by Flow Cytometry - Insights Unit Code 3287: Leukemia/Lymphoma Immunophenotyping by Flow Cytometry. Flow Cytometric Immunophenotyping Is Sensitive for the Early Diagnosis of De Novo Aggressive Natural Killer Cell Leukemia (ANKL): A Multicenter Retrospective Analysis. More info. Each persons condition will be unique. Disclaimer. "What is Immunophenotyping?". Retrieved on March 04, 2023 from https://www.news-medical.net/health/What-is-Immunophenotyping.aspx. Am J Clin Pathol. A bone marrow sample may be collected from the hip bone by a trained health care practitioner (Bone Marrow Aspiration and Biopsy). Available online at https://www.questdiagnostics.com/hcp/intguide/jsp/showintguidepage.jsp?fn=TG_Lymphoid_Neoplasms.htm. Furthermore, in difficult cases or those with limited material or poor histology, immunophenotypic analysis may be the only means of making a definitive diagnosis. MeSH -TCL-1 break-apart at 14q32, to exclude T-cell prolymphocytic leukemia in cases with CD4-positive T-cell lymphoproliferative disorder (phenotypic aberrancy or very tight CD4+ population with high CD4:CD8 ratio).
Sources: Serous effusions, pleural fluid, pericardial fluid, abdominal (peritoneal) fluid. An absolute CD8+ lymphocytosis correlates with disease progression and low expression of CD4 and CD8 (as found in autoimmune disease) The study was aimed to investigate the immunophenotypic and cytogenetic features of chronic lymphocytic leukemia (CLL) in order to provide an evidence for diagnosis and therapy. Pp 1633-1711. Federal government websites often end in .gov or .mil. If additional testing is required, it will be added per the algorithm to fully characterize a disease state with a charge per unique antibody tested. Acute myeloid leukemias (AMLs) are hematologic malignancies with varied molecular and immunophenotypic profiles, making them difficult to diagnose and classify. Cancers (Basel). eCollection 2016. (+632) 7110427 | (+632) 7110383 The lady explained that that meant I didn't have anything preconcerous, but she didn't see to know what it DID mean. Table 1. Tel19p/19q used to detect copy number abnormalities of chromosome 19, reveal a hybridization pattern within normal limits in 200 analyzed nuclei. Category filter: Show All (140)Most Common (2)Technology (21)Government & Military (34)Science & Medicine (22)Business (30)Organizations (68)Slang / Jargon (8) Acronym Definition NSA National Security Agency (US government) NSA Naval Support Activity NSA National Speakers Association NSA No Strings Attached NSA Naczelny Sad Administracyjny (Polish . American Society for Clinical Pathology; 2007; Betters DM: Use of flow cytometry in clinical practice.
Immunophenotyping by Flow Cytometry - Testing.com Novel Biological Insights and New Developments in Management of Burkitt Lymphoma and High-Grade B-Cell Lymphoma.
Diverse Immunophenotypic Abnormalities in Adult Patients with and transmitted securely. The volume of fluid necessary to phenotype the lymphocytes or blasts in serous effusions depends upon the cell count in the specimen. eCollection 2022. Owned and operated by AZoNetwork, 2000-2023. -, N Engl J Med. Clipboard, Search History, and several other advanced features are temporarily unavailable. Although diagnosticcriteria are well established, a No immunophenotypicmyeloid abnormalitieswere detectedin the healthy donor bone marrow aspirates or in the 10 remission bone marrow aspirates from patients with a history of nonmyeloid neoplasia Table 3, As mentioned, the immunophenotypicpanels used evolved during the study, and not all antigens This site needs JavaScript to work properly. If abnormal cells are present in the bloodstream, a blood sample is often used for flow cytometry immunophenotyping as it is easy to obtain and less invasive than other collection methods. ( 2011). This technique also helps identify or confirm the cell of origin in non-hematopoietic neoplasia. Classification of lymphoid neoplasms: the microscope as a tool for disease discovery. Available online at https://www.cancer.gov/cancertopics/factsheet/detection/laboratory-tests. Clipboard, Search History, and several other advanced features are temporarily unavailable. The antigens on specific leukemia or lymphoma cells may remain the same over time. 1985 Oct;79(4):445-54. doi: 10.1016/0002-9343(85)90031-2. Front Oncol. Smaller volumes can be used if there is a high cell count. Kruglov O, Johnson LDS, Minic A, Jordan K, Uger RA, Wong M, Sievers EL, Shou Y, Akilov OE. Bookshelf Atypical or abnormal cells can demonstrate . A pathologist, often one specializing in the study of blood diseases and/or blood cell cancers (a hematopathologist), will consider the results from the complete blood count (CBC), differential, blood smear, bone marrow findings, and flow cytometry immunophenotyping as well as other tests in order to provide a diagnostic interpretation. Immunophenotyping is widely used for the following reasons: Two types of tests are used in immunophenotyping: The choice of test is based on the type of sample: Heres a brief overview of the two types of test methods: In flow cytometry, the sample may range from blood, fluids in the body cavity (such as peritoneal or pleural fluids), bone marrow, or solid tissues in liquid media. According to the immunophenotype, MBL is labeled as chronic lymphocytic leukemia (CLL)-like (75% of cases), atypical CLL, and CD5-negative. Maecker, H. et. Creutzig U, Harbott J, Sperling C, Ritter J, Zimmermann M, Lffler H, Riehm H, Schellong G, Ludwig WD. . If possible, fluids other than spinal fluid should be anticoagulated with heparin (1 U/mL of fluid). Flow cytometry immunophenotyping is used primarily to help diagnose and classify blood cell cancers (leukemias and lymphomas) and to help guide their treatment. These plasma cells are negative for CD19. In these cases, LSC analysis is a methodology of choice because of its low sample requirements. Immunophenotyping, a common application in flow cytometry, allows multiple cell surface markers to be simultaneously characterized on a per-cell basis.Immunophenotyping can be difficult by flow cytometry, however, when only a small number of cells are available. In these cases, LSC analysis is a methodology of choice because of its low sample requirements. If the CT scan said that there are no significant abnormalities it means that nothing out of the ordinary was noted. A positive correlation was found between CD34+ and CD34 B-cell precursors (r . 2. 1. sharing sensitive information, make sure youre on a federal Leukemia & Lymphoma Society. 2020 Oct 13;4(19):4788-4797. doi: 10.1182/bloodadvances.2020002049. Accessibility al. How Is Childhood Leukemia Diagnosed? In addition, reflex testing may occur to fully characterize a disease state or clarify any abnormalities from the screening test. In this article, News-Medical talks to Sartorius about biosensing and bioprocessing in gene therapy, Recenti Prog Med. 2019 Aug 6;9:713. doi: 10.3389/fonc.2019.00713. Medscape Hematology. Accessed December 2014. Br J Haematol. Usually, 1 to 1.5 mL of spinal fluid is sufficient. Maturation-associated immunophenotypic abnormalities in bone marrow Background: Atypical lymphocytosis is a common peripheral blood abnormality seen not only in Epstein-Barr virus (EBV)-associated acute infectious mononucleosis but also in other conditions, including other viral infections, cancer, immune . Epub 2012 Sep 20. Diagnostic hematopathology has become an increasingly complex subspecialty, particularly with neoplastic disorders of blood and bone marrow.
Abnormal T-cell function in B-cell chronic lymphocytic leukaemia Hematopathology Patient Information (T676). Understanding Lab and Imaging Tests. This is the most common type of abnormal Pap smear. This form enables patients to ask specific questions about lab tests.
Immunophenotypic criteria for the diagnosis of non-Hodgkin's - PubMed This site needs JavaScript to work properly. Available online at https://www.merckmanuals.com/professional/sec11/ch142/ch142b.html. This test is appropriate for hematopoietic specimens only. Additional FISH or molecular testing may be recommended by the Mayo pathologist to facilitate diagnosis. The site is secure. Additional FISH or molecular testing may be recommended by the Mayo pathologist to facilitate diagnosis. 2021 Oct 15;13(10):12006-12015. eCollection 2021. Rosado FG, Morice WG, He R, Howard MT, Timm M, McPhail ED: Immunophenotypic features by multiparameter flow cytometry can help distinguish low grade B-cell lymphomas with plasmacytic differentiation from plasma cell proliferative disorders with an unrelated clonal B-cell process. Immunophenotyping, a common application in flow cytometry, allows multiple cell surface markers to be simultaneously characterized on a per-cell basis.Immunophenotyping can be difficult by flow cytometry, however, when only a small number of cells are available. The results from your immunophenotyping are compared to the pattern of antigens for normal cells as well as to patterns that are associated with abnormal cells (e.g., cells present with leukemias and lymphomas). Accessed January 2020. Based on these findings, we provide an objective marker based on clinical data for the definite diagnosis of ANKL. Diagnostic Value of Flow Cytometry in Cases with Myelodysplasia. JAMA Patient Page V301 (4) [On-line information]. -MYC break-apart at 8q24, with or without IGH-BCL2 t(14;18) and BCL6 break-apart at 3q27, for suspected high grade B-cell lymphomas, based on morphologic assessment and immunophenotype (usually CD10-positive). sharing sensitive information, make sure youre on a federal The prognostic value of immunophenotyping in AML is controversial [ 3]. Rahul E, Ningombam A, Acharya S, Tanwar P, Ranjan A, Chopra A. In the present study, we describe both quantitative and qualitative immunophenotypic abnormalities involving BM B-cells in MDS patients. ( 19952014). Second, unusual expression of surface antigens in ANKL cells was a prominent feature. News-Medical. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Anaplastic lymphoma kinase protein was detected in about 33% (3/9) of ALCLs examined by flow cytometric immunophenotyping (FCI); expression was validated by immunohistochemical analysis. Flow leukemia can be used in the case of an extensive range of leukemias that could be myeloid or lymphoid.
Standardizing immunophenotyping for the Human Immunology Project. Conclusion: Only 5 similar cases have been described previously. Large granular lymphocytic leukemia: a brief review.
Immunophenotyping - an overview | ScienceDirect Topics 1. Medscape Pediatrics: General Medicine. -A monoclonal Kappa B-cell population co-expression CD5, CD11c and CD23 is present. Careers. Miao Y, Zhang J, Chen Q, Xing L, Qiu T, Zhu H, Wang L, Fan L, Xu W, Li J. (+632) 7110427 | (+632) 7110383 Integrity Aesthetic Building, 788 Banawe Avenue, Quezon City, Philippines info@integrityaesthetic.ph The blood of an older child or adult normally contains some mature B cells, but circulating immature B cells are not normally present. The pivotal role of cytotoxic NK cells in mediating the therapeutic effect of anti-CD47 therapy in mycosis fungoides. Flow cytometry immunophenotyping may be useful in helping to diagnose, classify, treat and determine prognosis of these blood cell cancers. Leukemia Acute Lymphocytic (Adults). Li Y, Wei J, Mao X, Gao Q, Liu L, Cheng P, Liu L, Zhang X, Zhang K, Wang J, Zhu L, Zhou J, Zhang Y, Meng L, Sun H, Li D, Huang M, Huang W, Deng J, Zhang D. PLoS One. First, the CD45/linear side scatter gating of flow cytometry allows the initial identification of neoplastic subpopulations for additional immunophenotypic analysis in half of ANKL cases. Accessed January 2020. Epub 2020 Sep 9. -, N Engl J Med. Sometimes pieces of the abnormal myeloma protein are filtered through the kidney into the urine. Ngan BY, Picker LJ, Medeiros LJ, Warnke RA. Cheriyedath, Susha. Acute Leukemia. 2015 May;169(3):368-376. doi: 10.1111/bjh.13303, 5. Wittwera, C. and Brown, M. (2000).
LCMS - Overview: Leukemia/Lymphoma Immunophenotyping, Flow Cytometry While hundreds of antigens have been identified and have a unique CD number, only a small number of these are routinely used. In agreement with previous studies, no immunophenotypic features (other than monocytic differentiation) predicted the presence of an 11q23 rearrangement. This test has not been cleared or approved by the US Food and Drug Administration. The screening panel will be charged based on the number of markers tested (FIRST for first marker, ADD1 for each additional marker). We use cookies to enhance your experience.
Maturation-associated immunophenotypic abnormalities in bone marrow B 04 March 2023. Unable to load your collection due to an error, Unable to load your delegates due to an error. Nat Rev Immunol v12 (3): 191200. Wu, A. By continuing to browse this site you agree to our use of cookies. Accessed January 2020. An original cytospin preparation (preferably unstained) must be included with the spinal fluid specimen so correlative morphologic evaluation can occur. Shi M, Jevremovic D, Otteson GE, Timm MM, Olteanu H, Horna P: Single antibody detection of T-cell receptor alpha beta clonality by flow cytometry rapidly identifies mature T-cell neoplasms and monotypic small CD8-positive subsets of uncertain significance. The triage panel also includes antibodies to assess the number of CD3-positive T cells and CD16-positive/CD3-negative natural killer (NK) cells present. An official website of the United States government. These may be the first indication of a possible blood cell cancer. Trisomy 12 is the second most frequent aberration detected by fluorescence in situ hybridization at the time of diagnosis (10-25%), and it confers an intermediate prognostic risk, with a median time to . Map Of Southern Maine And New Hampshire, MeSH Available online at https://www.cancer.org/cancer/acute-lymphocytic-leukemia/detection-diagnosis-staging/how-diagnosed.html.
[Co-occurrence of t(8;21)(q22;q22) and t(9;22)(q34;q11) in a - PubMed It may be used in follow up to a complete blood count (CBC) and WBC differential that show an increased number of lymphocytes or the presence of immature blood cells or other abnormal cell counts. An abnormal karyotype was detected in 232 cases (54%). Accessed January 2020. Szary syndrome with multiple immunophenotypic aberrancies in tumor cells. Two or more immunophenotypic abnormalities were detected in 49 of 81 RCC patients (60%), and in 2 of 17 (v)SAA patients (12%). For solid tissue specimens, order LLPT / Leukemia/Lymphoma Immunophenotyping, Flow Cytometry, Tissue. News-Medical.
Now, if an adult has a small number of mature B cells but also has a large number of immature B cells which are positive for CD19 (remember, CD19 is a B-cell marker) and also positive for both CD34 and CD20 (which identifies those cells are both immature and abnormal), then the personhasan immature B-cell leukemia known as B-lymphoblastic leukemia. J Immunol.
Leukemia/Lymphoma Immunophenotyping, Flow Cytometry, Varies - St Clinical features, laboratory findings, morphologic, cytogenetic features, and Epstein-Barr virus status were important factors for diagnosing aggressive NK cell leukemia. Human herpesvirus-encoded kinase induces B cell lymphomas in vivo. 1. It depends. No abnormalities were detected for the other phenotypic markers analyzed, including 7.1 ( Table 2 ). Chronic active Epstein-Barr virus infection progresses to aggressive NK cell leukemia with a poor prognosis. For bone marrow specimens being evaluated for possible involvement by a myelodysplastic syndrome (MDS) or a myelodysplastic/myeloproliferative neoplasm (MDS/MPN), including chronic myelomonocytic leukemia (CMML), order MYEFL / Myelodysplastic Syndrome by Flow Cytometry, Bone Marrow. Spectrum and trigger identification of hemophagocytic lymphohistiocytosis in adults: A single-center analysis of 555 cases. Overall, del(13q14) and +12 were the most common abnormalities (39%), whereas del(11q13), del(17p13), and del(6q23) were detected only in 3, 1, and 0 cases, respectively. 122 cases were also subjected to karyotype analysis by Gbanding technology and abnormal karyotypes were detected in 69 out of 122 patients. Immunophenotypic and antigen receptor gene rearrangement analysis in T cell neoplasia.
The immunophenotype of different immature, myeloid and B-cell lineage Jiang NG, Jin YM, Niu Q, Zeng TT, Su J, Zhu HL. Aggressive natural killer (NK) cell leukemia (ANKL) is a systemic neoplastic proliferation of NK cells with an aggressive clinical course. lindalay. 2022. 1990 Oct;81(10):629-34. Upper endoscopy revealed a neoplastic growth at . The immunophenotype of adult acute myeloid leukemia: high frequency of lymphoid antigen expression and comparison of immunophenotype, French-American-British classification, and karyotypic abnormalities. The triage panel is initially performed to evaluate for monotypic B cells by kappa and lambda light chain expression, increased numbers of blast cells by CD34 and CD45 expression along with side scatter gating, and increased plasma cells by CD45 expression and side scatter gating. Hexosamine Biosynthetic Pathway Inhibition Leads to AML Cell Differentiation and Cell Death. No flow cytometric abnormalities were detected in CD4-positive T-cells from 10 control patients without lymphoproliferative disorders. (2018 March 12). Abnormal patterns of expression for at least one antigen was found in 91% of RA/RARS cases and in 74% of RAEB. Submit only 1 of the following specimens: Preferred: Yellow top (ACD solution A or B), Acceptable: Green top (sodium heparin) or lavender top (EDTA), Slides: If possible, include 5 to 10 unstained blood smears labeled with two unique identifiers. This site needs JavaScript to work properly. It can detect normal cells as well as abnormal cells whose pattern of markers are typically seen with specific types of leukemia and lymphoma. HHS Vulnerability Disclosure, Help If no abnormalities are detected by the initial panel, no further flow cytometric assessment will be performed unless otherwise indicated by specific features of the clinical presentation or prior laboratory results. Please enable it to take advantage of the complete set of features! This case suggested that chromosomal alterations may precede morphological, flow cytometric and clinical changes and accelerate progression of the disease. ALL RIGHTS RESERVED. [On-line information]. Curr Treat Options Oncol. Flow cytometry immunophenotyping may be performed on blood, bone marrow, or other samples to provide this additional information. This study prospectively analysed the relationships between immunophenotypic and cytogenetic features of blast cells in 432 acute non-lymphoblastic leukemias (ANLL) at presentation. ASCUS stands for Atypical Cells of Undetermined Significance,and basically means there were mild cellular changes and the the cause in unknown. News-Medical. http://www.cancer.gov/publications/dictionaries/cancer-terms?cdrid=341450, http://www.nature.com/leu/journal/v20/n7/full/2404242a.html, http://www.bloodjournal.org/content/96/3/870?sso-checked=true. 7 In summary, blasts of AMoL can be. Available online at https://www.arupconsult.com/Topics/LymphomaPhenotyping.html. The interpretation will be based on markers tested in increments of 2 to 8, 9 to 15, or 16 and greater.
What does 'no significant abnormalities' mean? Does it mean - Quora Cytometry B Clin Cytom. doi: 10.1371/journal.pone.0158827. Tietz Clinical Guide to Laboratory Tests, 4th Edition: Saunders Elsevier, St. Louis, MO. As the number of abnormal cells increase in a lymph node, the size of the lymph node increases. Viability 7AAD: 99%. She always had a keen interest in medical and health science. These abnormal populations, detected only by flow cytometry, comprised 1 and 2% of total white blood cells and were discrete CD4-dim CD26-negative T-cell populations.
no diagnostic immunophenotypic abnormalities detected low reading R03.1 . Cancer Immunol Immunother. These antigens are also used by the newer myeloma drugs to identify specific cancer cells. In agreement with previous studies, no immunophenotypic features (other than monocytic differentiation) predicted the presence of an 11q23 rearrangement. Unauthorized use of these marks is strictly prohibited. In her spare time, she loves to cook up a storm in the kitchen with her super-messy baking experiments. Chronic lymphocytic leukemia is an extremely heterogeneous disease and prognostic factors such as chromosomal abnormalities are important predictors of time to first treatment and survival. -Bone Marrow Staging for Known or Suspected Malignant Lymphoma Algorithm, -Acute Myeloid Leukemia: Testing Algorithm, -Acute Myeloid Leukemia: Relapsed with Previous Remission Testing Algorithm, -Acute Promyelocytic Leukemia: Guideline to Diagnosis and Follow-up, -Mast Cell Disorder: Diagnostic Algorithm, Bone Marrow, -Acute Leukemias of Ambiguous Lineage Testing Algorithm, Acute Leukemia -- Immunophenotyping, Flow Cytometry, Chronic Lymphocytic Leukemia, Immunophenotyping, Flow Cytometry, Flow Cytometry, Leukemia Immunophenotyping, Flow Cytometry, Lymphoma Immunophenotyping, Lymphoma Immunophenotyping by Flow Cytometry, GLL Panel - Leukemia Immunophenotyping (ALWAYS order LCMS), Granular Lymphocytic Leukemia (ALWAYS order LCMS), KIR Panel - Leukemia Immunophenotyping (ALWAYS order LCMS), LGL Panel - Leukemia Immunophenotyping (ALWAYS order LCMS), NK Panel - Leukemia Immunophenotyping (ALWAYS order LCMS), B-cell ALL minimal residual disease (MRD) detection. A laboratory report will typically include specific results from the tests as well as an analysis of what those results mean.